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Defytime TAM Spray 20ml


Defytime TAM Spray with Aqueous Propolis helps to improve biological health, while preventing dry mouth, tooth decay and gum disease naturally.

  • Made in New Zealand from natural ingredients and free of sugar and preservatives.
  • Promotes production of saliva as well as providing active anti-bacterial properties against tooth decay, gingivitis and bad breath.
  • TAM targets telomeres in cells, leading to younger and healthier cells.
  • TAM is the most effective anti-aging compound available.

Defytime TAM Spray is independently certified as meeting USA food safety standards. Download Report

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Telomerase Activating Molecule

Developed by Bill Andrews, Ph.D. of Sierra Sciences, LLC.) in 2014, TAM CO314818 is a state of the art Telomerase Activating Molecule (TAM) that counteracts and suppresses the fundamental cause of aging: telomere shortening.

By interfering with the action of telomerase inhibiting substances TAM CO314818 induces telomerase to function normally and to cause cell division to become more active leading to younger and healthier cells.

TAM is the most effective anti-aging compound available. All Defytime products feature the TAM logo to indicate they contain the TAM compound.


Water, Aqueous Propolis, Glycerin, Manuka Honey, Menthol, Sodium Bicarbonate, Flavour, Sucralose, Sodium Benzoate, Potassium Sorbate, Manuka Essential Oil, TAM CO314818.

Aqueous Propolis

Propolis is a natural compound made by bees. They collect resin from the buds of plants and mix it with enzymes to form a substance high in antioxidant and antibiotic properties. With its high levels of amino acids, minerals, vitamins and flavonoids and its anti-bacterial and anti-fungal properties, propolis is a powerful antiseptic agent and an initiator of the body’s own immune
defences, inhibiting the spread of unwanted disease.

Manuka Honey

Manuka Honey is a monofloral honey produced in New Zealand from the nectar of Manuka flowers. Manuka
Honey has many antibacterial properties as compared to normal honey. Manuka plants have historically been used by native Maori and early European settlers for medicinal purposes to treat colds, flu, and stomach aches. These special properties are unique to New Zealand
Manuka Honey.

Manuka Essential Oil

Manuka Oil is derived from the leaves of the Manuka tree and is widely known for its excellent health benefits. Manuka Oil is antibacterial in nature and helps to inhibit bacterial growth. The anti-fungal and anti-inflammatory properties of Manuka Oil can fight skin irritation and infection. Manuka Oil is also known to be anti-histaminic and anti-allergenic making it a good natural alternative to calm bites and stings.


For oral use. Shake before use. Apply 2-3 sprays directly on or under the tongue. Wait for 20 seconds before swallowing to absorb effectively. Apply twice a day (morning and evening).

Telomere Analysis Case Studies

Defytime is the only company publishing test results of people using and taking supplements containing the telomerase inducing activator TAM. Test cases have shown how the effects have been remarkable with telomere length increased and biological age reduced sometimes dramatically.

Learn more about Telomere Analysis Case Studies

Telomeres are an essential part of human cells that affect how our cells age.

Cell division plays a critical role in normal growth, maintenance and repair of all human tissues.

Telomeres are repeated sequences of DNA at the ends of each chromosome and are key genetic elements involved with the regulation of cell division. Telomeres shorten every time a cell divides, and once telomeres reach a critically short length, the cell either dies or stops dividing.

Telomerase is a naturally occurring enzyme that maintains telomeres and prevents them from shortening during cell division.

Learn more about TAM and telomere research

Bill Andrews, Ph.D.

CEO of Sierra Sciences / R&D for Defytime

Our cutting edge research is led by Dr. Bill Andrews. Dr. Andrews has worked in the biotech industry for over 35 years, focusing the last 20 years on finding ways to extend human lifespan through the intervention of telomere shortening in human cells.

Learn more about Bill Andrews, Ph.D.

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